COVID-19 and non-steroid anti-inflammatory drugs

Review of Anti-inflammatory and Immunosuppressive Drugs Used in COVID-19 Epidemic

Introduction: Immunosuppressive drugs are classified into different groups depending on the mechanism of action and are used in the control of acute and chronic inflammatory disorders. Considering the possibility of severe inflammatory complications such as acute respiratory failure and cytokine storm in the patients with COVID-19, there is a need to review the updated data on the effectiveness...

COVID-19: combining antiviral and anti-inflammatory treatments

The high affinity of baricitinib for the numb-associated kinase (NAK) family, its anti-inflammatory properties, with its advantageous pharmacokinetic properties, appear to make it a special case among the approved drugs.  In addition, the potential for combination therapy with baracitinib is high, because of its low plasma protein binding and minimal interaction with CYP enzymes and drug transp...

Non-steroidal anti-inflammatory drugs.

Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia.

The aim of this study was to evaluate the effects of anti-inflammatory intake on cognitive function in 7234 community-dwelling elderly persons. Cognitive performance, clinical diagnosis of dementia, and anti-inflammatory use were evaluated at baseline, and 2, 4, and 7 years later. Multivariate logistic regression analyses were adjusted for sociodemographic, behavioral, physical, mental health v...

Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease

Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such as smoking or use of Non Steroidal Anti-Inflammatory Drugs (NSAIDS). NSAIDS are among the most com...